DNA methylation has been newly discovered as a key controller in gene transcription too. Aberrant DNA methylation changes can cause a number of human diseases such as developmental diseases (ICF syndrome, Prader-Willi and Angelman syndromes etc), ag- ing related diseases (i.e. Alzheimer’s disease), heart disease, diabetes, and autoimmune diseases. Moreover, large amount of evidence implicated that DNA methylation is a key player in cancer development. Dr. Zhong will develop a suite of statistical models to broaden our understanding of how methylation patterns are established and maintained during normal development and under different environmental conditions. Click here to read more. Type of News/Audience: Departmental
